Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4830
|
| pubmed:dateCreated |
1987-12-23
|
| pubmed:abstractText |
Immunotoxins are conjugates of cell-reactive antibodies and toxins or their subunits. In this report, the chemistry, biology, pharmacokinetics, and anti-tumor effects of first generation immunotoxins; the preparation of improved second generation immunotoxins that display greater anti-tumor efficacy; and the role of genetic engineering in creating third-generation immunotoxins are discussed.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0036-8075
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
20
|
| pubmed:volume |
238
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1098-104
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:3317828-Animals,
pubmed-meshheading:3317828-Antineoplastic Agents,
pubmed-meshheading:3317828-Clinical Trials as Topic,
pubmed-meshheading:3317828-Humans,
pubmed-meshheading:3317828-Immunotoxins,
pubmed-meshheading:3317828-Neoplasms, Experimental,
pubmed-meshheading:3317828-Recombinant Proteins
|
| pubmed:year |
1987
|
| pubmed:articleTitle |
Redesigning nature's poisons to create anti-tumor reagents.
|
| pubmed:affiliation |
Department of Microbiology, University of Texas Southwestern Medical Center, Dallas 75235.
|
| pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Review,
Research Support, Non-U.S. Gov't
|