rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3-4
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pubmed:dateCreated |
1987-12-16
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pubmed:abstractText |
The influence of vaccination with an immunogenic K1 antigen of Escherichia coli on the course of pyelonephritis induced experimentally in rats by infection with Escherichia coli O2:K1:H4 was investigated. The immunogenic properties of K1 antigen are poor. A conjugate of K1 antigen with bovine serum albumin (BSA) was therefore tested. Preliminary experiments showed that the K1-BSA conjugate is immunogenic. Renal inflammatory activity in rats after retrograde infection was significantly reduced after vaccination of the animals with K1-BSA conjugate within six weeks of infection.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Bacterial,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Bacterial,
http://linkedlifedata.com/resource/pubmed/chemical/Bacterial Capsules,
http://linkedlifedata.com/resource/pubmed/chemical/Bacterial Vaccines,
http://linkedlifedata.com/resource/pubmed/chemical/Escherichia coli Vaccines,
http://linkedlifedata.com/resource/pubmed/chemical/Polysaccharides, Bacterial,
http://linkedlifedata.com/resource/pubmed/chemical/Serum Albumin, Bovine,
http://linkedlifedata.com/resource/pubmed/chemical/capsular polysaccharide K1
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0176-6724
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
265
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
408-19
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pubmed:dateRevised |
2009-6-8
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pubmed:meshHeading |
pubmed-meshheading:3314264-Animals,
pubmed-meshheading:3314264-Antibodies, Bacterial,
pubmed-meshheading:3314264-Antigens, Bacterial,
pubmed-meshheading:3314264-Bacterial Capsules,
pubmed-meshheading:3314264-Bacterial Vaccines,
pubmed-meshheading:3314264-Escherichia coli,
pubmed-meshheading:3314264-Escherichia coli Infections,
pubmed-meshheading:3314264-Escherichia coli Vaccines,
pubmed-meshheading:3314264-Female,
pubmed-meshheading:3314264-Polysaccharides, Bacterial,
pubmed-meshheading:3314264-Rats,
pubmed-meshheading:3314264-Rats, Inbred Strains,
pubmed-meshheading:3314264-Serum Albumin, Bovine,
pubmed-meshheading:3314264-Urinary Tract Infections
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pubmed:year |
1987
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pubmed:articleTitle |
Effect of immunization with Escherichia coli K1 antigen on the course of experimental infection of the urinary tract of the rat.
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pubmed:affiliation |
Institute of Microbiology, Medical School of the Wilhelm Pieck University, Rostock, GDR.
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pubmed:publicationType |
Journal Article
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