rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1987-12-1
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pubmed:abstractText |
Schistosoma mansoni schistosomula cultured in the presence of phospholipids showed a decreased sensitivity to the lethal complement-mediated action of anti-schistosome antibodies. Phosphatidyl choline, sphingomyelin and phosphatidyl ethanolamine had a protective action on the schistosomula transformed in vitro by passage through the skin or by a mechanical procedure. Phosphatidyl choline acted regardless of its fatty acid composition. Phosphatidyl serine and phosphatidic acid did not protect. Thus, it appears that phospholipids can play a role in parasite resistance to immune attack by cytotoxic antibodies and complement, and that this role is specific to certain phospholipid types.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Helminth,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Surface,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Complement System Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Immune Sera,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylcholines,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylethanolamines,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylserines,
http://linkedlifedata.com/resource/pubmed/chemical/Phospholipids,
http://linkedlifedata.com/resource/pubmed/chemical/Sphingomyelins
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0166-6851
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
133-42
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:3313040-Animals,
pubmed-meshheading:3313040-Antibodies, Helminth,
pubmed-meshheading:3313040-Antigens, Surface,
pubmed-meshheading:3313040-Cholesterol,
pubmed-meshheading:3313040-Complement System Proteins,
pubmed-meshheading:3313040-Fluorescent Antibody Technique,
pubmed-meshheading:3313040-Immune Sera,
pubmed-meshheading:3313040-Phosphatidic Acids,
pubmed-meshheading:3313040-Phosphatidylcholines,
pubmed-meshheading:3313040-Phosphatidylethanolamines,
pubmed-meshheading:3313040-Phosphatidylserines,
pubmed-meshheading:3313040-Phospholipids,
pubmed-meshheading:3313040-Schistosoma mansoni,
pubmed-meshheading:3313040-Sphingomyelins
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pubmed:year |
1987
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pubmed:articleTitle |
Protection by phospholipids of Schistosoma mansoni schistosomula against the action of cytotoxic antibodies and complement.
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pubmed:affiliation |
Unité de Biochimie des Antigènes, Institut Pasteur, Paris, France.
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pubmed:publicationType |
Journal Article
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