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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
1987-11-10
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pubmed:abstractText |
We investigated 46 cases of cutaneous lymphoma and pseudolymphoma by immunohistochemical methods using a panel of monoclonal antibodies. Of the cutaneous T cell lymphomas, 2 did not show the classic helper phenotype but revealed a predominance of suppressor cells in one case and of immature thymocytes in the other. Cutaneous B cell lymphomas of low-grade malignancy were characterized by the presence of completely developed T zones between the B cell areas. B cell lymphomas of high-grade malignancy revealed an immunohistologically homogeneous infiltrate. Cutaneous pseudolymphomas can be classified in T cell pseudolymphomas (lymphocytic infiltration, lymphomatoid papulosis) and B cell pseudolymphomas. Lymphadenosis cutis benigna with germinal center cell differentiation was clearly distinguishable from other B cell pseudolymphomas, which are considered to comprise mainly peripheral B lymphocytes. Immunohistological methods are obviously useful in the classification of lymphoproliferative diseases of the skin and can make a contribution to increasing our understanding of them.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0017-8470
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
461-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3308776-Antibodies, Monoclonal,
pubmed-meshheading:3308776-Antigens, Neoplasm,
pubmed-meshheading:3308776-Antigens, Surface,
pubmed-meshheading:3308776-B-Lymphocytes,
pubmed-meshheading:3308776-Biopsy,
pubmed-meshheading:3308776-Humans,
pubmed-meshheading:3308776-Immunoenzyme Techniques,
pubmed-meshheading:3308776-Lymphoma,
pubmed-meshheading:3308776-Skin Neoplasms,
pubmed-meshheading:3308776-T-Lymphocytes
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pubmed:year |
1987
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pubmed:articleTitle |
[Immunohistochemical classification of cutaneous lymphomas and pseudolymphomas].
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pubmed:affiliation |
Universitätsklinik für Dermatologie und Venerologie Graz.
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
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