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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
|
pubmed:dateCreated |
1987-10-19
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pubmed:abstractText |
Thirty patients who had curative surgery for sigmoid and rectal carcinoma were studied by immunoscintigraphy using a new monoclonal antibody: B72.3 radiolabeled with Iodine-131 (I-131) or Indium-111 (In-111). Results were compared with other conventional diagnostic procedures such as computed tomography, ultrasound, endoscopy, and tumor markers. Seven patients had local recurrences and/or distant metastases. Immunoscintigraphy identified all local recurrences (five cases) that were confirmed by CT and was able to localize three of five liver metastases (two false-negatives). Furthermore, immunoscintigraphy also recorded a false-positive. Preliminary use of B72.3 shows good potential for the evaluation and detection of neoplastic sites.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0012-3706
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
683-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3304885-Adult,
pubmed-meshheading:3304885-Aged,
pubmed-meshheading:3304885-Antibodies, Monoclonal,
pubmed-meshheading:3304885-Endoscopy,
pubmed-meshheading:3304885-False Negative Reactions,
pubmed-meshheading:3304885-False Positive Reactions,
pubmed-meshheading:3304885-Female,
pubmed-meshheading:3304885-Follow-Up Studies,
pubmed-meshheading:3304885-Humans,
pubmed-meshheading:3304885-Male,
pubmed-meshheading:3304885-Middle Aged,
pubmed-meshheading:3304885-Neoplasm Recurrence, Local,
pubmed-meshheading:3304885-Rectal Neoplasms,
pubmed-meshheading:3304885-Sigmoid Neoplasms,
pubmed-meshheading:3304885-Tomography, X-Ray Computed,
pubmed-meshheading:3304885-Ultrasonography
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pubmed:year |
1987
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pubmed:articleTitle |
Immunoscintigraphy in the follow-up of patients operated on for carcinoma of the sigmoid and rectum. Preliminary report with a new monoclonal antibody: B72.3.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|