Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
31-32
pubmed:dateCreated
1987-9-15
pubmed:abstractText
Although intraindividual comparisons of commonly used human standard combination insulins have not been made, pharmacodynamic differences between preparations in the by now no vast insulin market have been highlighted. The action of five bio- or semisynthetic human insulins of all four manufacturers using the same galenic formula and with a fixed normal insulin content of 20-30% was tested at equal dosages in type IIa and type IIb diabetics with differing residual pancreatic secretion. No differences were demonstrated in onset, maximum or duration of action. The blood-sugar lowering effect of the preparations is particularly marked in the late morning hours and may, if not counteracted by adequate carbohydrate intake, lead to hypoglycaemia. Duration of action of the preparations depends on the individual extent of endogenous pancreatic insulin reserves.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0012-0472
pubmed:author
pubmed:issnType
Print
pubmed:day
31
pubmed:volume
112
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1209-12
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
[Treatment of type II diabetes using homologous intermediate-acting insulin combinations. Comparison of the effectiveness of 5 commonly used preparations].
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, English Abstract, Randomized Controlled Trial