Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1987-8-10
pubmed:abstractText
Miniature swine fed a high-cholesterol, high-fat diet demonstrated heterogeneity in the extent of coronary artery disease. Plasma cholesterol or lipoprotein concentrations as well as other known risk factors accounted for little of this heterogeneity. However, the majority of the variability could be accounted for by the familial predisposition to develop cardiovascular disease in the individual animal kindreds. This study strongly suggests that the enhanced rate of development of coronary atherosclerotic disease during hypercholesterolemia is more critically modulated by previously unrecognized genetic actors than by absolute plasma cholesterol concentrations.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0021-9150
pubmed:author
pubmed:issnType
Print
pubmed:volume
65
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
167-72
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
A familial basis for the heterogeneity in coronary atherosclerotic disease.
pubmed:publicationType
Journal Article