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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
1988-5-13
|
| pubmed:abstractText |
Recent molecular genetic experiments conducted in the USA and The Netherlands have isolated specific mutations in human lung cancer cells. These data implicate the activation of the K-ras oncogene in the pathogenesis of adenocarcinoma of the lungs of heavy smokers and the deletion of DNA from the short arm of chromosome 3 in small-cell and non-small-cell carcinoma of the lung. The implications of these results are discussed and explained in the light of current DNA-manipulative technology which is now available in RSA.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0256-9574
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
2
|
| pubmed:volume |
73
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
406-8
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:3282328-Animals,
pubmed-meshheading:3282328-Cell Transformation, Neoplastic,
pubmed-meshheading:3282328-Fibroblasts,
pubmed-meshheading:3282328-Genes, ras,
pubmed-meshheading:3282328-Humans,
pubmed-meshheading:3282328-Lung Neoplasms,
pubmed-meshheading:3282328-Mice,
pubmed-meshheading:3282328-Smoking
|
| pubmed:year |
1988
|
| pubmed:articleTitle |
Smoking, oncogenes and human lung cancer. A review of recent laboratory evidence linking smoking and lung cancer.
|
| pubmed:affiliation |
Department of Pharmacology, University of Stellenbosch, Parowvallei.
|
| pubmed:publicationType |
Journal Article
|