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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1988-11-14
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pubmed:abstractText |
A retrospective study of 23 cases of nonlymphoblastic T cell lymphomas with no features of either mycosis fungoides (MF) or Sézary syndrome (SS) was carried out. 6 patients exhibited cutaneous (or mucous) lesions and are presented herein. There was no detectable visceral or node involvement except in 1 patient. 3 cases were immunologically proven to be of peripheral T cell origin. Except T cell lymphomas in Japan and in the Caribbean area, the frequency of prevalent skin involvement is reportedly very low in non-MF/SS non lymphoblastic T cell lymphomas. However, it is likely that this frequency has been underestimated in Western countries. The histologic features of our cases run the heterogeneous spectrum of recently described node-based forms of peripheral T cell lymphomas: 'angioimmunoblastic lymphadenopathy with dysproteinemia'-like lymphoma, large T cell lymphoma, multilobulated cell lymphoma, T zone lymphoma. The histologic pattern of skin infiltration was different from that of MF/SS. One case was initially suggestive of a pseudolymphoma and had a prolonged evolution but the other patients suffered from rapid extracutaneous involvement and fatal evolution with resistance to treatment. Cutaneous plasmacytomas were seen in 1 case. Hence, certain cutaneous T cell lymphomas exhibit histologic, immunological and developmental features similar to those of node-based peripheral T cell lymphomas but different from those of MF/SS.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0011-9075
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
177
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
82-97
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3262542-Aged,
pubmed-meshheading:3262542-Diagnosis, Differential,
pubmed-meshheading:3262542-Female,
pubmed-meshheading:3262542-Humans,
pubmed-meshheading:3262542-Lymph Nodes,
pubmed-meshheading:3262542-Lymphoma,
pubmed-meshheading:3262542-Male,
pubmed-meshheading:3262542-Middle Aged,
pubmed-meshheading:3262542-Mycosis Fungoides,
pubmed-meshheading:3262542-Sezary Syndrome,
pubmed-meshheading:3262542-Skin Neoplasms,
pubmed-meshheading:3262542-T-Lymphocytes
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pubmed:year |
1988
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pubmed:articleTitle |
Non lymphoblastic T cell lymphomas with prevalent skin involvement different from mycosis fungoides or Sézary's syndrome. A retrospective study of 6 cases in Europe.
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pubmed:affiliation |
Service de Dermatologie, Hôpital Ste-Marguerite, Marseille, France.
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pubmed:publicationType |
Journal Article
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