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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1988-9-2
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pubmed:abstractText |
The distribution and the functional capacity of special subpopulations was examined by means of monoclonal anti-Lyt-1.2-, anti-Lyt-2.2-, anti-L3T4- and anti-Thy-1.2-antibodies. The proportion of Lyt-2+-cells increased after allogeneic stimulation of spleen cells compared with the Lyt-1+-cells. The proportion of L3T4+-cells did not change by allogeneic stimulation. Lyt-2- cells which were negatively selected by monoclonal antibody and complement effected the Con A stimulated 3H-thymidine incorporation of a spleen cell culture in a different way depending on their state of differentiation. While Lyt-2--cells selected from a fresh prepared spleen cell suspension increased the 3H thymidine incorporation, Lyt-2--cells selected from allogeneically stimulated cell suspension act as suppressor cells. The results demonstrate the dynamics in the functional capacity of the Lyt-2--T cell subpopulation depending on their state of differentiation.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0323-4398
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
27-34
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3261121-Animals,
pubmed-meshheading:3261121-Antibodies, Monoclonal,
pubmed-meshheading:3261121-Antigens, Differentiation, T-Lymphocyte,
pubmed-meshheading:3261121-Concanavalin A,
pubmed-meshheading:3261121-Lymphocyte Activation,
pubmed-meshheading:3261121-Mice,
pubmed-meshheading:3261121-Mice, Inbred Strains,
pubmed-meshheading:3261121-Spleen,
pubmed-meshheading:3261121-T-Lymphocytes
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pubmed:year |
1988
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pubmed:articleTitle |
[Functional capacity of T-cell subpopulations of the mouse. Effect of unstimulated and allogenic stimulated T-cell subpopulations on Con A stimulation of splenic lymphocytes].
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pubmed:affiliation |
Institut für Biochemie, Wilhelm-Pieck-Universität Rostock.
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pubmed:publicationType |
Journal Article,
English Abstract
|