Linked Life Data

3237700

Source:http://linkedlifedata.com/resource/pubmed/id/3237700

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1989-5-10
pubmed:abstractText
The DNA content of the various neoplastic elements of 12 Feulgen-stained metaplastic breast carcinomas was measured by image analysis. Spindle cell, osseous, chondroid, rhabdomyoid, or squamous cell metaplastic elements comprised at least half of each neoplasm in which an invasive ductal carcinoma component also was identified. The epithelial elements in all of the neoplasms were aneuploid, as was the metaplastic component in 11 of the cases. Multiple stem cell lines were detected in the ductal carcinoma component in 4 cases and in the metaplastic components in 5 cases. Our findings lend support to the view that metaplastic elements are derived from malignant epithelial cells, rather than from benign stromal cells. Neither aneuploidy nor the presence of multiple stem cell lines was a useful predictor of the biologic behavior of these 12 neoplasms.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0893-3952
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
193-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Cytophotometric measurements of metaplastic carcinoma of the breast: correlation with pathologic features and clinical behavior.
pubmed:affiliation
Department of Pathology, University of Michigan, Ann Arbor.
pubmed:publicationType
Journal Article