Linked Life Data

3229466

Source:http://linkedlifedata.com/resource/pubmed/id/3229466

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-4-13
pubmed:abstractText
The aim of the present study was to evaluate the neurochemical changes in the levels of gangliosides and glycogen of the cerebral hemisphere, cerebellum, brain stem and spinal cord following the intraperitoneal (ip) injection of the organophosphate pesticide methyl parathion (1.0 mg, 1.5 mg and 2.0 mg/kg) to each rat of the experimental group daily for 7 days. A remarkable dose-related depletion in the concentration of gangliosides was discernible in all the regions of the CNS. Also, the contents of glycogen exhibited a decrement in different parts of the brain with all the 3 dose-schedules following methyl parathion toxicosis. The results suggest that the levels of gangliosides and glycogen are affected dose-dependently in various regions of the rat brain and spinal cord.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0232-1513
pubmed:author
pubmed:issnType
Print
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
61-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Dose-related neurochemical changes in the levels of gangliosides and glycogen in various regions of the rat brain and spinal cord following methyl parathion administration.
pubmed:affiliation
Interdisciplinary Brain Research Centre, Jawaharlal Nehru Medical College, Aligarh Muslim University, India.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't