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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
1989-3-8
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pubmed:abstractText |
Porphyrin isomer examinations have been performed in two patients with Rotor syndrome (RS), one patient with Gilbert-Meulengracht syndrome and 12 patients with alcohol toxic cholestasis. Under both conditions, cholestasis and RS, total urinary coproporphyrin excretion as well as coproporphyrin isomer I was relatively and absolutely increased. Despite the different degree of the increase of coproporphyrin isomer I excretion between RS (69 vs. 72%) and cholestasis (47% on average), there are single cases with a coproporphyrin isomer I portion around 60%. In such cases, the differential diagnosis is quite difficult, so that the diagnosis "Rotor syndrome" should never be gained by one distinct examination; it is a diagnosis performed by exclusion of other diseases.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Bilirubin,
http://linkedlifedata.com/resource/pubmed/chemical/Coproporphyrins,
http://linkedlifedata.com/resource/pubmed/chemical/Porphyrins,
http://linkedlifedata.com/resource/pubmed/chemical/coproporphyrin I,
http://linkedlifedata.com/resource/pubmed/chemical/coproporphyrin III
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0044-2771
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
416-20
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:3218284-Adult,
pubmed-meshheading:3218284-Aged,
pubmed-meshheading:3218284-Alcoholism,
pubmed-meshheading:3218284-Bilirubin,
pubmed-meshheading:3218284-Cholestasis, Intrahepatic,
pubmed-meshheading:3218284-Coproporphyrins,
pubmed-meshheading:3218284-Diagnosis, Differential,
pubmed-meshheading:3218284-Humans,
pubmed-meshheading:3218284-Jaundice, Chronic Idiopathic,
pubmed-meshheading:3218284-Liver Function Tests,
pubmed-meshheading:3218284-Male,
pubmed-meshheading:3218284-Porphyrins
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pubmed:year |
1988
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pubmed:articleTitle |
[Rotor syndrome: relevance of the determination of coproporphyrin isomers in the urine in comparison with intrahepatic (alcohol-induced) cholestasis].
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pubmed:affiliation |
Abteilung für Klinische Biochemie im Fachbereich Humanmedizin, Universität Marburg.
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports,
Research Support, Non-U.S. Gov't
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