Linked Life Data

3207543

Source:http://linkedlifedata.com/resource/pubmed/id/3207543

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1989-2-17
pubmed:abstractText
The effects of diazepam on antroduodenal motility, gastric pH and gastric emptying rate were investigated in 10 volunteers. Gastric emptying was assessed using paracetamol absorption and antroduodenal motility and pH by means of a perfused multilumen tube. On the first study day, the volunteers received paracetamol in phase I after the occurrence of one complete interdigestive motility complex (IDMC). Diazepam was given on the second study day at the beginning of the first phase I and paracetamol was given one IDMC later. The rate of absorption correlated with motility (P less than 0.03). Some volunteers were fast absorbers on the first study day and slow on the second, indicating that absorption rate is not constant, but dependent on gastroduodenal motility. Diazepam tended to increase the gastric emptying rate and enhanced the amplitude of contractions and the motility index during phase II (P less than 0.02). Gastric pH increased after ingestion of diazepam (P less than 0.05).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0007-0912
pubmed:author
pubmed:issnType
Print
pubmed:volume
61
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
712-9
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Gastrointestinal motility and gastric pH and emptying following ingestion of diazepam.
pubmed:affiliation
Department of Anaesthesiology and Surgical Gastroenterology, University Hospital, Aarhus, Denmark.
pubmed:publicationType
Journal Article