Linked Life Data

3197780

Source:http://linkedlifedata.com/resource/pubmed/id/3197780

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4-5
pubmed:dateCreated
1989-1-26
pubmed:abstractText
Long-lived recombinant inbred lines, some of which have mean and maximum life spans up to 70% longer than wild type, were used in these analyses. Longer life results from a slower exponential rate of increase in mortality. General motor activity decreases with chronological age in all genotypes; this decay in general motor activity is a biomarker of aging in that it is a predictor of maximum life span. The aging process has also been dissected into component processes. The length of development and the length of reproduction are unrelated to increased life span; lengthened life is due entirely to an increase in post-reproductive life span. Development, reproduction, and life span are each under independent genetic control. General motor activity and life span share at least one common rate-determining genetic component.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0531-5565
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
281-95
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Long-lived lines of Caenorhabditis elegans can be used to establish predictive biomarkers of aging.
pubmed:affiliation
Department of Molecular Biology and Biochemistry, University of California, Irvine 92717.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.