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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
1989-1-9
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pubmed:abstractText |
Discs of human amnion prepared from nine women delivered by elective caesarean section at term were incubated with and without purified human amniotic fluid surfactant (9 micrograms lipid P/ml), and the output of prostaglandin E (PGE) was estimated by radioimmunoassay. Surfactant stimulated the release of PGE from 3.8 (SD 2.9) to 5.4 (SD 2.5) pmol/mg dry weight/3 h (P less than 0.01). Arachidonic acid accounted for 2% of the fatty acids of surfactant lecithin. These results show that surfactant has a stimulatory effect on amniotic PGE production and that it is an important source of arachidonic acid in amniotic fluid.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0306-5456
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
95
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1013-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3191038-Amnion,
pubmed-meshheading:3191038-Amniotic Fluid,
pubmed-meshheading:3191038-Arachidonic Acids,
pubmed-meshheading:3191038-Cesarean Section,
pubmed-meshheading:3191038-Dose-Response Relationship, Drug,
pubmed-meshheading:3191038-Female,
pubmed-meshheading:3191038-Fetus,
pubmed-meshheading:3191038-Humans,
pubmed-meshheading:3191038-Pregnancy,
pubmed-meshheading:3191038-Prostaglandins E,
pubmed-meshheading:3191038-Stimulation, Chemical,
pubmed-meshheading:3191038-Surface-Active Agents,
pubmed-meshheading:3191038-Time Factors
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pubmed:year |
1988
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pubmed:articleTitle |
Surfactant stimulates prostaglandin E production in human amnion.
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pubmed:affiliation |
University of Oxford, Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Headington.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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