Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1988-12-22
pubmed:abstractText
Although calcium supplements are widely used in the treatment of osteoporosis their beneficial effect is not conclusively established. The biochemical effects of a calcium supplement (1 g/d) given for between 6 and 36 months were studied in 20 postmenopausal osteoporotic women who had normal calcium absorption. The mean fasting urinary hydroxyproline/creatinine ratio decreased from 0.024 +/- 0.002 to 0.016 +/- 0.001 (P less than 0.005) indicating a significant reduction in bone resorption. The mean plasma alkaline phosphatase fell from 85 +/- 4 U/l to 73 +/- 3 U/l (P less than 0.005), probably representing a secondary reduction in bone formation following the inhibition of bone resorption. There was no significant change in calcium absorption. These results support the concept that calcium supplementation is useful in the treatment of postmenopausal osteoporosis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0954-3007
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
775-8
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Biochemical effects of calcium supplementation in postmenopausal osteoporosis.
pubmed:affiliation
Department of Medicine, Royal Adelaide Hospital, South Australia.
pubmed:publicationType
Journal Article