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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1988-11-9
|
| pubmed:abstractText |
We studied unselected, hepatitis B surface antigen (HBsAg)-positive parenteral drug abusers for antibody to hepatitis D virus (anti-HD) and antibody to human immunodeficiency virus (HIV). The prevalences of anti-HD and antibody to HIV were 67% and 58%, respectively, and there was no association between positivity for these two markers. In a logistic regression model, anti-HD was associated with older age (P = .001), longer duration of drug abuse (P = .045), and the presence of liver disease (P = .002). Antibody to HIV was associated with a younger age (P = .003) and increased serum globulin levels (P less than .001). In patients infected with HIV, the severity of hepatic dysfunction remained correlated with anti-HD. In anti-HD-positive patients, most indices of hepatic dysfunction were similar whether or not antibody to HIV was present, but serum aspartate aminotransferase levels were significantly higher in patients with both anti-HD and antibody to HIV. (124 +/- 16 vs. 74 +/- 11, P less than .05).
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0022-1899
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
158
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
795-803
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:3171227-AIDS-Related Complex,
pubmed-meshheading:3171227-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:3171227-Adult,
pubmed-meshheading:3171227-Age Factors,
pubmed-meshheading:3171227-Antibodies, Viral,
pubmed-meshheading:3171227-DNA, Viral,
pubmed-meshheading:3171227-Female,
pubmed-meshheading:3171227-HIV Antibodies,
pubmed-meshheading:3171227-Hepatitis B,
pubmed-meshheading:3171227-Hepatitis B Surface Antigens,
pubmed-meshheading:3171227-Hepatitis B virus,
pubmed-meshheading:3171227-Hepatitis D,
pubmed-meshheading:3171227-Hepatitis Delta Virus,
pubmed-meshheading:3171227-Humans,
pubmed-meshheading:3171227-Male,
pubmed-meshheading:3171227-New York City,
pubmed-meshheading:3171227-Regression Analysis,
pubmed-meshheading:3171227-Substance-Related Disorders
|
| pubmed:year |
1988
|
| pubmed:articleTitle |
Hepatitis D virus and human immunodeficiency virus antibodies in parenteral drug abusers who are hepatitis B surface antigen positive.
|
| pubmed:affiliation |
Department of Medicine, Beth Israel Medical Center, New York, New York 10003.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|