Linked Life Data

315865

Source:http://linkedlifedata.com/resource/pubmed/id/315865

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1980-2-15
pubmed:abstractText
The effect of synthetic melanocyte-stimulating hormones (MSH) on urinary excretion of sodiu, potassium and water was studied in hamsters. Synthetic alpha-MSH and synthetic human beta-MSH showed a marked natriuretic and diuretic effect depending on the dosage of hormone. The natriuretic effect of both hormones was approximately equal and did not parallel the magnitude of the melanocyte-stimulating activity of the investigated peptides. Both peptides showed also a milder kaliuretic effect independent on their dose. The rise of the sodium/potassium index in urine was significant after both peptides. Bilateral adrenalectomy increased further the natriuresis induced by alpha-MSH, while it did not affect the effect o MSH on diuresis and kaliuresis. Changes in urinary excretion of sodium and potassium are considered to be consequence of direct renal action of MSH.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0013-7200
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
145-52
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Natriuretic and kaliuretic effect of melanocyte-stimulating hormones in hamsters.
pubmed:publicationType
Journal Article, Comparative Study