rdf:type |
|
lifeskim:mentions |
umls-concept:C0016964,
umls-concept:C0022173,
umls-concept:C0035820,
umls-concept:C0076729,
umls-concept:C0135201,
umls-concept:C0229671,
umls-concept:C0346647,
umls-concept:C0680730,
umls-concept:C0702242,
umls-concept:C0920688,
umls-concept:C1148554
|
pubmed:dateCreated |
1989-2-23
|
pubmed:abstractText |
The clinical usefulness of tissue polypeptide antigen, galactosyltransferase II and pancreatic oncofetal antigen was evaluated in detecting pancreatic cancer and in differentiating this malignancy from chronic pancreatitis and other diseases (mainly of the liver and biliary tract) which may enter in differential diagnosis. TPA seems to be the most sensitive among these indices in detecting pancreatic cancer and appears to discriminate this malignancy quite satisfactorily from chronic pancreatitis. It is also frequently pathological in a number of other diseases and is influenced by the presence of liver dysfunction. GT II and POA do not grossly differ from TPA in specificity, but they appear to be less sensitive. Both are frequently pathological in hepato-biliary diseases. All these markers seem, therefore, to be of limited value in the diagnosis of pancreatic cancer.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/Aspartate Aminotransferases,
http://linkedlifedata.com/resource/pubmed/chemical/Galactosyltransferases,
http://linkedlifedata.com/resource/pubmed/chemical/Isoenzymes,
http://linkedlifedata.com/resource/pubmed/chemical/Peptides,
http://linkedlifedata.com/resource/pubmed/chemical/Serum Albumin,
http://linkedlifedata.com/resource/pubmed/chemical/Tissue Polypeptide Antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological,
http://linkedlifedata.com/resource/pubmed/chemical/oncofetal antigens
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0169-4197
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
3 Suppl 1
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
S95-100
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3145303-Antigens, Neoplasm,
pubmed-meshheading:3145303-Aspartate Aminotransferases,
pubmed-meshheading:3145303-Chronic Disease,
pubmed-meshheading:3145303-Galactosyltransferases,
pubmed-meshheading:3145303-Humans,
pubmed-meshheading:3145303-Isoenzymes,
pubmed-meshheading:3145303-Pancreatic Neoplasms,
pubmed-meshheading:3145303-Pancreatitis,
pubmed-meshheading:3145303-Peptides,
pubmed-meshheading:3145303-Serum Albumin,
pubmed-meshheading:3145303-Tissue Polypeptide Antigen,
pubmed-meshheading:3145303-Tumor Markers, Biological
|
pubmed:year |
1988
|
pubmed:articleTitle |
Tissue polypeptide antigen, galactosyltransferase isoenzyme II and pancreatic oncofetal antigen serum determination: role in pancreatic cancer diagnosis.
|
pubmed:affiliation |
Istituto di Medicina Interna (Cattedra di Malattie Apparato Digerente), Policlinico Universitario, Padova, Italy.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|