Linked Life Data

3135809

Source:http://linkedlifedata.com/resource/pubmed/id/3135809

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1988-9-2
pubmed:abstractText
Paired helical filaments, which are present in the brain of Alzheimer's disease patients have been isolated and characterized. Treatment of the filaments with reducing agents and detergents extracts several proteins from these structures. The remaining filaments are composed mainly of a protein with molecular weight of 33 kDa suggesting that this protein is the core component of these filaments. Peptide mapping using trypsin and endoproteinase Arg-C revealed that the 33 kDa protein, was a modified form of tau protein present in normal human brain.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0006-291X
pubmed:author
pubmed:issnType
Print
pubmed:day
29
pubmed:volume
154
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
660-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
A modified form of microtubule-associated tau protein is the main component of paired helical filaments.
pubmed:affiliation
Centro de Biología Molecular (CSIC-UAM), Universidad Autónoma, Madrid, Spain.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't