Linked Life Data

3117897

Source:http://linkedlifedata.com/resource/pubmed/id/3117897

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1987-12-3
pubmed:abstractText
Immunoglobulin replacement therapy in the form of intravenous immunoglobulin (IVIgG) is clearly of benefit in primary hypogammaglobulinaemia and related disorders involving antibody deficiency. However, its use in the prevention of infection in other conditions is controversial and needs to be clarified. IVIgG therapy may be of benefit in selected patients with IgG subclass deficiency, and with a proven history of recurrent upper respiratory tract infections. IVIgG therapy may also benefit infants with AIDS and recurrent bacterial infections, but is only rarely of value in cases of adult AIDS. The use of 'normal' IVIgG from unselected blood donors to treat viral infections, infections due to gram negative organisms, or to neutralise endotoxin, is probably not indicated on theoretical and practical grounds, and because of the high cost. IVIgG preparations derived from plasma donations selected for high specific antibody levels to the relevant microorganism will probably be of greater benefit than normal IVIgG in patients with specific infections.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0163-4453
pubmed:author
pubmed:issnType
Print
pubmed:volume
15 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
21-8
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
The use of intravenous immunoglobulin for the treatment of infection: an overview.
pubmed:affiliation
Edinburgh and South East Scotland Blood Transfusion Service, U.K.
pubmed:publicationType
Journal Article, Review