| pubmed-article:3100957 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3100957 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:3100957 | lifeskim:mentions | umls-concept:C0026473 | lld:lifeskim |
| pubmed-article:3100957 | lifeskim:mentions | umls-concept:C0596402 | lld:lifeskim |
| pubmed-article:3100957 | lifeskim:mentions | umls-concept:C1522405 | lld:lifeskim |
| pubmed-article:3100957 | pubmed:issue | 6101 | lld:pubmed |
| pubmed-article:3100957 | pubmed:dateCreated | 1987-2-26 | lld:pubmed |
| pubmed-article:3100957 | pubmed:abstractText | Interleukin-2 (IL-2), originally described as a growth factor required for sustained proliferation of T cells in vitro is a glycoprotein hormone of known structure which appears to be important for the generation of immune responses in vivo. As well as T lymphocytes, B lymphocytes and large granular lymphocytes with natural killer activity (NK cells) can also respond to IL-2. The action of IL-2 seemed to be limited specifically to lymphocytes, however, and the term 'T-lymphocytotrophic hormone' was used. Here we provide evidence that human monocytes display a substantially increased cytotoxic activity as a direct and rapid response to human recombinant IL-2 but not to human recombinant glycosylated interferon-gamma (IFN-gamma) or lipopolysaccharide. Our results reveal a previously unknown function of IL-2 and suggest its possible involvement in monocyte-T cell interactions. | lld:pubmed |
| pubmed-article:3100957 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3100957 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3100957 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3100957 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3100957 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:3100957 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3100957 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3100957 | pubmed:issn | 0028-0836 | lld:pubmed |
| pubmed-article:3100957 | pubmed:author | pubmed-author:WardPP | lld:pubmed |
| pubmed-article:3100957 | pubmed:author | pubmed-author:AshersonG LGL | lld:pubmed |
| pubmed-article:3100957 | pubmed:author | pubmed-author:FiersWW | lld:pubmed |
| pubmed-article:3100957 | pubmed:author | pubmed-author:MalkovskýMM | lld:pubmed |
| pubmed-article:3100957 | pubmed:author | pubmed-author:NorthMM | lld:pubmed |
| pubmed-article:3100957 | pubmed:author | pubmed-author:GanMM | lld:pubmed |
| pubmed-article:3100957 | pubmed:author | pubmed-author:LovelandBB | lld:pubmed |
| pubmed-article:3100957 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3100957 | pubmed:volume | 325 | lld:pubmed |
| pubmed-article:3100957 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3100957 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3100957 | pubmed:pagination | 262-5 | lld:pubmed |
| pubmed-article:3100957 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:3100957 | pubmed:meshHeading | pubmed-meshheading:3100957-... | lld:pubmed |
| pubmed-article:3100957 | pubmed:meshHeading | pubmed-meshheading:3100957-... | lld:pubmed |
| pubmed-article:3100957 | pubmed:meshHeading | pubmed-meshheading:3100957-... | lld:pubmed |
| pubmed-article:3100957 | pubmed:meshHeading | pubmed-meshheading:3100957-... | lld:pubmed |
| pubmed-article:3100957 | pubmed:meshHeading | pubmed-meshheading:3100957-... | lld:pubmed |
| pubmed-article:3100957 | pubmed:meshHeading | pubmed-meshheading:3100957-... | lld:pubmed |
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| pubmed-article:3100957 | pubmed:meshHeading | pubmed-meshheading:3100957-... | lld:pubmed |
| pubmed-article:3100957 | pubmed:articleTitle | Recombinant interleukin-2 directly augments the cytotoxicity of human monocytes. | lld:pubmed |
| pubmed-article:3100957 | pubmed:publicationType | Journal Article | lld:pubmed |
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