Switch to
Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1986-12-18
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pubmed:abstractText |
The ultrastructural and immunohistochemical characteristics of a high-grade epithelioid angiosarcoma of the scalp are reported. By light microscopy, the neoplasm simulated a poorly differentiated carcinoma, either primary or metastatic from some occult site. Immunohistochemical study, using a specific antibody against factor VIII-related antigen, was positive when direct immunofluorescence was applied to frozen specimens of the neoplasm. Application of immunoperoxidase (avidin-biotin complex method) on paraffin-embedded tissue using the same antibody was negative. Ultrastructually, the neoplasm had a prominent cytoskeleton of intermediate filaments, numerous pinocytotic vesicles, small intercellular lumina with microvilli on their surfaces, and characteristic intracytoplasmic vacuoles. A brief discussion of the differential diagnostic features is made.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0193-1091
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
8
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
411-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3096158-Aged,
pubmed-meshheading:3096158-Antigens,
pubmed-meshheading:3096158-Cytoplasm,
pubmed-meshheading:3096158-Factor VIII,
pubmed-meshheading:3096158-Fluorescent Antibody Technique,
pubmed-meshheading:3096158-Hemangiosarcoma,
pubmed-meshheading:3096158-Humans,
pubmed-meshheading:3096158-Immunoenzyme Techniques,
pubmed-meshheading:3096158-Male,
pubmed-meshheading:3096158-Microscopy, Electron,
pubmed-meshheading:3096158-Neoplasm Recurrence, Local,
pubmed-meshheading:3096158-Scalp,
pubmed-meshheading:3096158-Skin Neoplasms,
pubmed-meshheading:3096158-von Willebrand Factor
|
pubmed:year |
1986
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pubmed:articleTitle |
High-grade epithelioid angiosarcoma of the scalp. An immunohistochemical and ultrastructural study.
|
pubmed:publicationType |
Journal Article,
Case Reports
|