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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1986-9-17
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pubmed:abstractText |
Conflicting results have emerged from studies using oral and rectal disodium cromoglycate (DSCG) in inflammatory bowel disease. In the present double-blind study, 43 patients with active ulcerative proctosigmoiditis received either placebo (n = 22) or 600 mg DSCG (n = 21) rectally as enemas for eight weeks. Assessment was made from clinical investigations, endoscopy, laboratory tests, biopsies, and diary cards. No statistically significant differences in bowel frequency, rectal bleeding, general well-being, abdominal pain, and severity and extent of the disease were found between the groups during the study. There was no significant change in the histologic parameters. No side-effect was encountered. It is concluded that DSCG did not improve symptoms or inflammatory changes in ulcerative proctosigmoiditis.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0001-6101
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
219
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
497-500
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3090860-Adolescent,
pubmed-meshheading:3090860-Adult,
pubmed-meshheading:3090860-Aged,
pubmed-meshheading:3090860-Clinical Trials as Topic,
pubmed-meshheading:3090860-Colitis,
pubmed-meshheading:3090860-Cromolyn Sodium,
pubmed-meshheading:3090860-Double-Blind Method,
pubmed-meshheading:3090860-Enema,
pubmed-meshheading:3090860-Female,
pubmed-meshheading:3090860-Humans,
pubmed-meshheading:3090860-Male,
pubmed-meshheading:3090860-Middle Aged,
pubmed-meshheading:3090860-Proctocolitis,
pubmed-meshheading:3090860-Rectum,
pubmed-meshheading:3090860-Tablets
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pubmed:year |
1986
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pubmed:articleTitle |
Local disodium cromoglycate is ineffective in ulcerative proctosigmoiditis.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
|