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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1986-6-27
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pubmed:abstractText |
Sixty-four patients were randomized prior to pelvic radiotherapy into one of three dietary groups: the control group maintained a regular diet except that they drank at least 480 cc of milk daily; the lactose-restricted group was placed on a lactose-restricted diet; and the lactase group drank at least 480 cc of milk with lactase enzyme added to hydrolyze 90% of the lactose. The patients kept records of their stool frequency and the number of diphenoxylate tablets required to control their diarrhea during a 5 week course of standard whole pelvis irradiation. The data does not support the concept that one of the mechanisms of radiation-induced diarrhea associated with pelvic irradiation is a reduction the ability of the intestine to hydrolyze ingested lactose due to the effect of the radiation on the small intestine. There was not a significant difference in stool frequency or diphenoxylate usage among the dietary groups.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0360-3016
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
12
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
789-92
|
pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3086261-Animals,
pubmed-meshheading:3086261-Diarrhea,
pubmed-meshheading:3086261-Dietary Carbohydrates,
pubmed-meshheading:3086261-Diphenoxylate,
pubmed-meshheading:3086261-Female,
pubmed-meshheading:3086261-Humans,
pubmed-meshheading:3086261-Hydrolysis,
pubmed-meshheading:3086261-Lactose,
pubmed-meshheading:3086261-Lactose Intolerance,
pubmed-meshheading:3086261-Male,
pubmed-meshheading:3086261-Middle Aged,
pubmed-meshheading:3086261-Milk,
pubmed-meshheading:3086261-Pelvic Neoplasms,
pubmed-meshheading:3086261-Radiation Injuries,
pubmed-meshheading:3086261-Random Allocation,
pubmed-meshheading:3086261-beta-Galactosidase
|
pubmed:year |
1986
|
pubmed:articleTitle |
Failure of lactose-restricted diets to prevent radiation-induced diarrhea in patients undergoing whole pelvis irradiation.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|