Linked Life Data

3084669

Source:http://linkedlifedata.com/resource/pubmed/id/3084669

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1986-6-24
pubmed:abstractText
Between November 1981 and October 1984, 48 of 3,456 clinical isolates of Streptococcus faecalis that were studied showed high-level (greater than 2,000 micrograms/ml) resistance to gentamicin. A case-control study comparing patients with gentamicin-susceptible (MIC less than 64 micrograms/ml) and -resistant S. faecalis infections showed significant associations (P less than .01) between the development of infection with highly gentamicin-resistant S. faecalis and prior antimicrobial therapy (particularly with cephalosporins or aminoglycosides), perioperative antibiotic prophylaxis, prior surgical procedures, and longer hospitalization. All highly resistant strains appeared to be nosocomial since 12 cases were clustered on a surgical floor and in a burn unit. In vitro transfer of gentamicin resistance by filter mating was observed for 44 of 48 isolates. The use of plasmid content as an epidemiological marker suggested nosocomial transmission and exogenous acquisition of S. faecalis.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0022-1899
pubmed:author
pubmed:issnType
Print
pubmed:volume
153
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1075-83
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
High-level resistance to gentamicin in Streptococcus faecalis: risk factors and evidence for exogenous acquisition of infection.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.