Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6512
pubmed:dateCreated
1986-3-11
pubmed:abstractText
Thirteen non-diabetic renal transplant recipients had various aspects of carbohydrate and lipid metabolism studied before and after conversion from cyclosporin A to azathioprine. No patient had a glucose tolerance test result diagnostic of diabetes mellitus before conversion, and there was no change in fasting glucose or immunoreactive insulin values after conversion. There was, however, a fall in the area under the curve of the glucose tolerance test values after conversion. Furthermore, fasting serum cholesterol and triglyceride concentrations fell significantly after conversion. No change in the concentration of high density lipoprotein cholesterol was detected. These findings suggest that cyclosporin A is associated with an inferior lipid profile as compared with azathioprine, which may be important in patients with transplants given the drug long term.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0267-0623
pubmed:author
pubmed:issnType
Print
pubmed:day
4
pubmed:volume
292
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
16
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Alterations in lipid and carbohydrate metabolism attributable to cyclosporin A in renal transplant recipients.
pubmed:publicationType
Journal Article, Comparative Study