Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1989-7-21
pubmed:abstractText
Cytokines are soluble molecules with many cells as the source of their origin and as targets for their actions. They are pleiotropic in their biological functions. Some cytokines are distinct with respect to their molecular structure yet they have overlapping biological properties (Interleukin 1 and tumor necrosis factors). Others are structurally distinct and often have contrasting biological activities (e.g. tumor necrosis factors and transforming growth factor-beta). In this article I have briefly reviewed the molecular and biological properties of four cytokines that appears to play an important role in the pathogenesis of certain immunoinflammatory disorders. It is also to be stressed that there are additional cytokines (e.g. granulocyte-monocyte colony stimulating factors, interleukin 2, interferons etc.) that could also play a role in the pathogenesis of immunoinflammatory disorders.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0301-3847
pubmed:author
pubmed:issnType
Print
pubmed:volume
76
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
189-201
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Cytokines: molecular and biological characteristics.
pubmed:affiliation
Division of Basic and Clinical Immunology, University of California, Irvine 92717.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't