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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1978-5-17
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pubmed:abstractText |
The relationship between the binding patterns of soybean agglutinin, peanut agglutinin (both in their native (unaggregated) form and in their polymerized form), and of Phaseolus vulgaris leucoagglutinin, to neuraminidase-treated lymphocytes from different sources, and the mitogenic activity of these lectins, was studied. In all cases investigated, binding of a lectin to lymphocytes which resulted in stimulation was a positive cooperative process. Our findings support the assumption that clustering of receptors and conformational changes in membrane structure are prerequisites for mitogenic stimulation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0006-3002
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
21
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pubmed:volume |
508
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
137-46
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:305262-Animals,
pubmed-meshheading:305262-B-Lymphocytes,
pubmed-meshheading:305262-Drug Resistance,
pubmed-meshheading:305262-Hydrocortisone,
pubmed-meshheading:305262-Kinetics,
pubmed-meshheading:305262-Lectins,
pubmed-meshheading:305262-Male,
pubmed-meshheading:305262-Mice,
pubmed-meshheading:305262-Neuraminidase,
pubmed-meshheading:305262-Rats,
pubmed-meshheading:305262-T-Lymphocytes
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pubmed:year |
1978
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pubmed:articleTitle |
Cooperativity of lectin binding to lymphocytes, and its relevance to mitogenic stimulation.
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pubmed:publicationType |
Journal Article
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