Linked Life Data

3051291

Source:http://linkedlifedata.com/resource/pubmed/id/3051291

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1988-11-10
pubmed:abstractText
Of 58 patients in Leogane, Haiti, infected with Wuchereria bancrofti and treated with diethylcarbamazine citrate (DEC-C) at 6 mg/kg per day for 12 days (= 72 mg/kg), 38 (66%) of 58 continued to harbor low numbers of circulating microfilariae (median microfilariae could be demonstrated in 7 (37%) of 19 patients, with a median microfilarial density of 8 mf/ml. Three patients who continued to have circulating microfilariae after two courses of DEC-C were treated a third time. Two (67%) of the three remained microfilaria positive, both with 1 mf/ml. The results of this study clearly indicate that a high percentage of persons infected with W. bancrofti and treated with one or multiple courses of DEC-C may continue to have circulating microfilariae after treatment. We suspect that these low-level reservoir carriers substantially contribute to the transmission of filariasis and may well account for the resurgence of infection levels following control efforts.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0177-2392
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
128-30
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Persistence of microfilaremia in bancroftian filariasis after diethylcarbamazine citrate therapy.
pubmed:affiliation
Internatinal Collaboration in Infectious Diseases Research Program, Tulane University Medical Center, New Orleans, Louisiana.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.