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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1978-3-21
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pubmed:abstractText |
The development of lymphocytic leukemia with a rapidly fatal clinical course is reported in a patient with kappa light-chain multiple myeloma treated with alkeran. The leukemic cells lacked the ultrastructural features of plasma cells but bore readily detectable B-cell markers and resembled lymphocytes under the light, transmission, and scanning electron microscopes. The leukemic phase is perhaps best defined as lymphocytic and probably represents a variant of plasma cell leukemia, in which the cells showed a degree of dedifferentiation from plasma cells to B lymphocytes. The possible relation between these 2 proliferative processes is discussed and the nature of leukemias developing in cases of plasma cell myeloma is briefly reviewed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0361-8609
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
153-63
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:304668-B-Lymphocytes,
pubmed-meshheading:304668-Female,
pubmed-meshheading:304668-Humans,
pubmed-meshheading:304668-Immunoelectrophoresis,
pubmed-meshheading:304668-Leukemia, Lymphoid,
pubmed-meshheading:304668-Middle Aged,
pubmed-meshheading:304668-Multiple Myeloma,
pubmed-meshheading:304668-Receptors, Antigen, B-Cell,
pubmed-meshheading:304668-Rosette Formation
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pubmed:year |
1977
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pubmed:articleTitle |
Multiple myeloma terminating in lymphocytic leukemia with B-lymphocyte membrane markers.
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pubmed:publicationType |
Journal Article,
Case Reports
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