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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1988-10-6
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pubmed:abstractText |
Plasma renin activity (PRA) was determined in a group of 610 Japanese schoolchildren aged 10-14 years in order to investigate the relationship between PRA distribution and a family history of hypertension. Plasma renin activity was higher in the subjects with a family history of hypertension (FH+) than in those without a family history of hypertension (FH-). Systolic blood pressure (SBP) was also higher in the FH+ group than in the FH- group. The FH- group showed a significant negative correlation between PRA and SBP (boys, r = -0.254, P less than 0.01; girls, r = -0.225, P less than 0.01), whereas the FH+ group showed no correlation between PRA and blood pressure. These results suggested that schoolchildren with a family history of hypertension might have an enhanced renin-aldosterone (R-A) system, resulting in elevation of blood pressure.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0263-6352
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
489-93
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3045203-Adolescent,
pubmed-meshheading:3045203-Blood Pressure,
pubmed-meshheading:3045203-Child,
pubmed-meshheading:3045203-Female,
pubmed-meshheading:3045203-Humans,
pubmed-meshheading:3045203-Hypertension,
pubmed-meshheading:3045203-Japan,
pubmed-meshheading:3045203-Male,
pubmed-meshheading:3045203-Prospective Studies,
pubmed-meshheading:3045203-Renin,
pubmed-meshheading:3045203-Renin-Angiotensin System,
pubmed-meshheading:3045203-Rural Population
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pubmed:year |
1988
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pubmed:articleTitle |
An epidemiological study of plasma renin activity in schoolchildren in Japan: distribution and its relation with family history of hypertension.
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pubmed:affiliation |
Department of Hygiene, Hyogo College of Medicine, Japan.
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pubmed:publicationType |
Journal Article
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