Linked Life Data

304333

Source:http://linkedlifedata.com/resource/pubmed/id/304333

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1978-2-23
pubmed:abstractText
The electrophoretic mobility (EPM) of lymphoid cells from the spleen and thymus of A/Sn mice was studied after a single injection of a double-stranded synthetic polynucleotide, poly-A:U. The proportion of spleen T lymphocytes with a high EPM increased markedly and rose to 80% of the total cell population on the 3rd day. The percentage of high mobility lymphocytes began to decrease on the 4th day, but normal values were not reached until the 15th day. Important variations in electrophoretic distribution profiles of the thymic cells were also observed after poly-A:U inoculation. In the untreated athymic Nude mice, 5% of the spleen cells have a high mobility and are presumed to be T-cell precursors. After a single inoculation of poly-A:U, the percentage of these cells increased to 18%. This increase correlated well with the increase in theta-positive spleen cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-4910
pubmed:author
pubmed:issnType
Print
pubmed:volume
128
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1039-52
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:articleTitle
Changes in lymphocyte subpopulations in mice receiving a single injection of poly-A:U.
pubmed:publicationType
Journal Article