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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1987-9-21
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pubmed:abstractText |
Na+-K+-dependent ouabain-sensitive ATPase and Mg2+-ATPase have been assayed in the erythrocyte membranes of control subjects and in uncontrolled type I (insulin-dependent) diabetics. A decrease in Na+-K+-ATPase activity was observed in the patients that was significantly correlated with glycemia. The Mg2+-ATPase was increased moderately, and no correlation with glycemia was found. To study the in vivo effect of insulin, ATPase activities were measured in uncontrolled diabetics before and after a 24-h continuous insulin perfusion administered by means of an artificial pancreas. ATPase activities were corrected after normalization of glycemia. It therefore seems that glycemia and/or insulinemia are involved in the regulation of erythrocyte Na+-K+ ouabain-sensitive ATPase and to a lesser extent in that of Mg2+-dependent ATPase.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0012-1797
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
991-5
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:3038641-Adenosine Triphosphatases,
pubmed-meshheading:3038641-Adult,
pubmed-meshheading:3038641-Aged,
pubmed-meshheading:3038641-Ca(2+) Mg(2+)-ATPase,
pubmed-meshheading:3038641-Diabetes Mellitus, Type 1,
pubmed-meshheading:3038641-Erythrocyte Membrane,
pubmed-meshheading:3038641-Female,
pubmed-meshheading:3038641-Humans,
pubmed-meshheading:3038641-Insulin,
pubmed-meshheading:3038641-Insulin Infusion Systems,
pubmed-meshheading:3038641-Male,
pubmed-meshheading:3038641-Middle Aged,
pubmed-meshheading:3038641-Sodium-Potassium-Exchanging ATPase
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pubmed:year |
1987
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pubmed:articleTitle |
In vivo insulin effect on ATPase activities in erythrocyte membrane from insulin-dependent diabetics.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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