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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6127
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pubmed:dateCreated |
1987-8-14
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pubmed:databankReference |
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pubmed:abstractText |
We have cloned and sequenced cDNAs of the strychnine-binding subunit of the rat glycine receptor, a neurotransmitter-gated chloride channel protein of the CNS. The deduced polypeptide shows significant structural and amino-acid sequence homology with nicotinic acetylcholine receptor proteins, indicating that there is a family of genes encoding neurotransmitter-gated ion channels.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0028-0836
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
328
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
215-20
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3037383-Amino Acid Sequence,
pubmed-meshheading:3037383-Animals,
pubmed-meshheading:3037383-Binding Sites,
pubmed-meshheading:3037383-Cloning, Molecular,
pubmed-meshheading:3037383-DNA,
pubmed-meshheading:3037383-Membrane Proteins,
pubmed-meshheading:3037383-Multigene Family,
pubmed-meshheading:3037383-Protein Binding,
pubmed-meshheading:3037383-Protein Conformation,
pubmed-meshheading:3037383-Rats,
pubmed-meshheading:3037383-Receptors, Glycine,
pubmed-meshheading:3037383-Receptors, Neurotransmitter,
pubmed-meshheading:3037383-Receptors, Nicotinic,
pubmed-meshheading:3037383-Sequence Homology, Nucleic Acid,
pubmed-meshheading:3037383-Strychnine,
pubmed-meshheading:3037383-Tissue Distribution
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pubmed:articleTitle |
The strychnine-binding subunit of the glycine receptor shows homology with nicotinic acetylcholine receptors.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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