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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1987-2-4
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pubmed:abstractText |
The effect of neomycin on the Herpes Simplex Virus (HSV) type 1 and 2 infection of baby hamster kidney cells was studied. Neomycin concentrations of 3 mM or more caused a more than 90% inhibition of HSV 1 proliferation, while it had no effect on HSV 2 proliferation, measured as plaque-forming units. Furthermore, neomycin must be present at the time of infection in order to exert full effect, addition 1 hour postinfection was comparable to untreated cells. This indicates that neomycin may specifically interfere with very early stages of HSV 1 infection.
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pubmed:commentsCorrections | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0006-291X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
26
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pubmed:volume |
141
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
198-203
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:3026374-Animals,
pubmed-meshheading:3026374-Cell Line,
pubmed-meshheading:3026374-Cricetinae,
pubmed-meshheading:3026374-Dose-Response Relationship, Drug,
pubmed-meshheading:3026374-Neomycin,
pubmed-meshheading:3026374-Simplexvirus,
pubmed-meshheading:3026374-Time Factors,
pubmed-meshheading:3026374-Viral Plaque Assay,
pubmed-meshheading:3026374-Virus Replication
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pubmed:year |
1986
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pubmed:articleTitle |
Evidence that neomycin inhibits HSV 1 infection of BHK cells.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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