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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1986-7-9
|
| pubmed:abstractText |
The polypeptide hormones gastrin and cholecystokinin are structurally related, having the identical pentapeptide GWMDF located at their C-terminus. The precursors to these two hormones also show amino acid homology, suggesting that they may have a common ancestral origin. Recombinant DNA clones corresponding to gene fragments encoding human gastrin and cholecystokinin were used to determine their respective chromosomal localization by analyzing human-rodent cell lines. We have assigned the cholecystokinin gene to human chromosome 3q12-3pter and the gastrin gene to chromosome 17q.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0340-6717
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
73
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
77-80
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:3011648-Animals,
pubmed-meshheading:3011648-Cell Line,
pubmed-meshheading:3011648-Cholecystokinin,
pubmed-meshheading:3011648-Chromosome Mapping,
pubmed-meshheading:3011648-Chromosomes, Human, 1-3,
pubmed-meshheading:3011648-Chromosomes, Human, 16-18,
pubmed-meshheading:3011648-Cricetinae,
pubmed-meshheading:3011648-DNA, Recombinant,
pubmed-meshheading:3011648-DNA Restriction Enzymes,
pubmed-meshheading:3011648-Gastrins,
pubmed-meshheading:3011648-Genes,
pubmed-meshheading:3011648-Humans,
pubmed-meshheading:3011648-Hybrid Cells,
pubmed-meshheading:3011648-Mice
|
| pubmed:year |
1986
|
| pubmed:articleTitle |
The genes for human gastrin and cholecystokinin are located on different chromosomes.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|