Linked Life Data

3006115

Source:http://linkedlifedata.com/resource/pubmed/id/3006115

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
224
pubmed:dateCreated
1986-3-28
pubmed:abstractText
Eleven sural nerve biopsies from nine acromegalic patients, with and without peripheral neuropathy, were examined utilizing routine sections, single teased fibres and electron microscopy. The initial basic pathological lesion in both groups consisted of demyelination combined with hypertrophic formations affecting the Schwann cell system of the small diameter fibres. Second biopsies from two patients with neuropathy demonstrate the natural history of the lesion. The progression to eventual end-stage neuropathy is documented and is due to the marked onion bulb formation. Recovery is unlikely. Our findings indicate that the development of peripheral neuropathy in acromegaly is a serious complication. Deterioration, both clinically and pathologically, can be expected if the growth hormone remains persistently elevated.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0033-5622
pubmed:author
pubmed:issnType
Print
pubmed:volume
57
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
833-42
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Natural history of acromegalic peripheral neuropathy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't