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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
|
pubmed:dateCreated |
1986-4-3
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pubmed:abstractText |
A polymorphic locus flanking the 5' end of the insulin gene was studied in 154 unrelated Japanese diabetic and nondiabetic subjects. A predominance of the small allele was found with the following frequency: of 64 nondiabetic subjects, only 3 of 128 alleles were of the large class (2%); none of 78 alleles were of the large class in 39 Type 1 (insulin-dependent) diabetic subjects, and 4 of 102 alleles (4%) were of the large class in 51 Type 2 (non-insulin-dependent) diabetic subjects. The very low frequency of large allele may relate to the lower prevalence of atherosclerosis in Japanese. However, this possibility requires further examination.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0012-186X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
28
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
911-3
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:3005097-Alleles,
pubmed-meshheading:3005097-DNA Restriction Enzymes,
pubmed-meshheading:3005097-Diabetes Mellitus, Type 1,
pubmed-meshheading:3005097-Diabetes Mellitus, Type 2,
pubmed-meshheading:3005097-Genes,
pubmed-meshheading:3005097-Genotype,
pubmed-meshheading:3005097-Humans,
pubmed-meshheading:3005097-Insulin,
pubmed-meshheading:3005097-Polymorphism, Genetic
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pubmed:year |
1985
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pubmed:articleTitle |
Restriction fragment length polymorphism of the insulin gene region in Japanese diabetic and non-diabetic subjects.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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