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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1986-2-28
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pubmed:abstractText |
Zoster immunoglobulin (ZIG) was given for prophylaxis to 95 neonates born to mothers with perinatal varicella. The treatment had no influence on the clinical attack rate; 48 (50%) of the children developed varicella. However, the ZIG treatment clearly influenced the course of the disease for newborns at particular risk, i.e. when maternal varicella developed within 4 days before and 2 days after delivery. Of 41 such neonates, 21 (51%) contracted varicella with an incubation mean time of 11 days. 13 of the 21 developed a very mild chickenpox (no fever, less than or equal to 20 pocks), 6 had a mild to normal disease, and 2 (10%) had more severe infections; none died or got sequelae after the disease. These results should be compared with the expected rate of complications in non-treated neonates in the defined risk group, where the mortality among those contracting varicella has been reported to be as high as about 30%.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0036-5548
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
343-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3003888-Antibodies, Viral,
pubmed-meshheading:3003888-Antibody Formation,
pubmed-meshheading:3003888-Chickenpox,
pubmed-meshheading:3003888-Female,
pubmed-meshheading:3003888-Gestational Age,
pubmed-meshheading:3003888-Herpesvirus 3, Human,
pubmed-meshheading:3003888-Humans,
pubmed-meshheading:3003888-Infant, Newborn,
pubmed-meshheading:3003888-Male,
pubmed-meshheading:3003888-Pregnancy,
pubmed-meshheading:3003888-Pregnancy Complications, Infectious
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pubmed:year |
1985
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pubmed:articleTitle |
Effect of zoster immunoglobulin for varicella prophylaxis in the newborn.
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pubmed:publicationType |
Journal Article
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