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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
1985-12-30
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pubmed:abstractText |
Analysis of three different nusA mutant strains suggests that the expression of the nusA-infB operon of Escherichia coli is regulated autogenously by the nusA gene product, a protein known to mediate transcription termination and antitermination. The cellular amounts of NusA and IF2 (infB) proteins are enhanced by a nusAts mutation which causes reduced transcription-termination activity. A nusAam mutant carrying the am ts suppressor, supFts6, overproduces the IF2 protein when the amount of NusA protein is reduced by the thermal inactivation of the supFts6. A modified form of NusA with the cat protein of Mr of 24 000 attached to the C terminus of NusA is overproduced compared to the wild-type NusA and causes the overproduction of IF2.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0378-1119
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
36
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
189-93
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2998933-Bacterial Proteins,
pubmed-meshheading:2998933-Escherichia coli,
pubmed-meshheading:2998933-Genes, Bacterial,
pubmed-meshheading:2998933-Homeostasis,
pubmed-meshheading:2998933-Mutation,
pubmed-meshheading:2998933-Operon,
pubmed-meshheading:2998933-Species Specificity,
pubmed-meshheading:2998933-Temperature
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pubmed:year |
1985
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pubmed:articleTitle |
Evidence for autoregulation of the nusA-infB operon of Escherichia coli.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|