Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1985-12-2
|
pubmed:abstractText |
The addition of polymorphonuclear leukocytes (PMNL) to human fibroblasts infected with varicella-zoster virus (VZV) resulted in a reduced virus yield. The reduction was greater when antibodies specific for VZV were added to the system. Addition of VZV-specific antibodies without PMNL also reduced virus yield, but a 10-fold greater concentration of antibodies was required to effect the same reduction. PMNL adhered to and formed rosettes around VZV-infected cells. By electron microscopy, it was possible to observe activation of PMNL incubated with VZV-infected fibroblasts. Activated PMNL extended cytoplasmic projections toward virions and had vacuoles containing virions in various stages of digestion.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0300-5526
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
24
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
119-24
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:2997077-Cells, Cultured,
pubmed-meshheading:2997077-Fibroblasts,
pubmed-meshheading:2997077-Herpesvirus 3, Human,
pubmed-meshheading:2997077-Humans,
pubmed-meshheading:2997077-Microscopy, Electron,
pubmed-meshheading:2997077-Neutrophils,
pubmed-meshheading:2997077-Phagocytosis,
pubmed-meshheading:2997077-Rosette Formation,
pubmed-meshheading:2997077-Viral Plaque Assay
|
pubmed:year |
1985
|
pubmed:articleTitle |
Interaction between polymorphonuclear leukocytes and varicella-zoster virus-infected cells.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|