Linked Life Data

2989296

Source:http://linkedlifedata.com/resource/pubmed/id/2989296

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1985-8-5
pubmed:abstractText
Using a perfusion chamber, we examined the behavior of individual amebae in increasing and decreasing temporal gradients of cAMP. We demonstrated that amebae respond to increasing temporal gradients of cAMP with stimulated motility and to corresponding decreasing temporal gradients with depressed motility. Depressed motility observed in decreasing temporal gradients corresponded to the inhibited levels observed when cAMP was applied at constant concentrations. These results were consistent with a simple model for the motile behavior of amebae in an early aggregation territory in which nondissipating waves of cAMP originate at the aggregation center and travel outward periodically. We conclude that chemotactically responsive amebae can assess whether a temporal gradient of chemoattractant is increasing or decreasing in the absence of a spatial gradient, and can adjust their motility accordingly.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/2989296-173312, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989296-222770, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989296-4340476, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989296-4560688, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989296-4615133, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989296-479314, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989296-5389735, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989296-5535143, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989296-6088555, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989296-6280593, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989296-6299820, http://linkedlifedata.com/resource/pubmed/commentcorrection/2989296-944707
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0021-9525
pubmed:author
pubmed:issnType
Print
pubmed:volume
101
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-5
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Dictyostelium amebae alter motility differently in response to increasing versus decreasing temporal gradients of cAMP.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.