Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1985-6-21
pubmed:abstractText
The first bicarbonate pool sizes and kinetic data necessary for the interpretation of substrate oxidation studies have been determined in six fed, nonacidotic infants, ages 2.5 to 5 months. Following an intravenous bolus of NaH13CO3 (50 mumol/kg), breath samples were collected over 240 min for the analysis of breath 13CO2. Each breath 13CO2 disappearance curve was fitted to a multicompartmental bicarbonate model previously derived in adults. The mean sizes of the three bicarbonate pools were: 7.4 +/- 0.8 mmol/kg (central pool), 15.1 +/- 4.8 mmol/kg (rapidly exchanging peripheral pool), and 8.8 +/- 3.5 mmol/kg (slowly exchanging peripheral pool). The mean percentage dose recovery was 57 +/- 10%. The pool sizes suggested that extensive metabolic exchange of carbon between HCO3- and organic metabolites occurred in the infant.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0031-3998
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
358-63
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Characterization of HCO3-/CO2 pool sizes and kinetics in infants.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.