Linked Life Data

2981423

Source:http://linkedlifedata.com/resource/pubmed/id/2981423

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1985-2-20
pubmed:abstractText
The effects of malnutrition on the viral replication pattern and severity of clinical disease were examined in suckling mice infected with mouse rotavirus (MRV). The infection in malnourished animals was characterized by a significant decrease in the minimal infectious dose and in the incubation period of the onset of diarrhea, when compared to well-nourished controls. Viral replication in the dispersed enterocytes was observed 6-12 hr earlier, fecal viral shedding peaked significantly earlier, and the clinical disease appeared to be more severe in the malnourished animals than in the controls. These observations provide strong evidence for malnutrition-induced alterations in the pathogenesis of rotaviral infection in vivo.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0037-9727
pubmed:author
pubmed:issnType
Print
pubmed:volume
178
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
85-90
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Effect of malnutrition on rotavirus infection in suckling mice: kinetics of early infection.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't