| pubmed-article:2970507 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2970507 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:2970507 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
| pubmed-article:2970507 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:2970507 | lifeskim:mentions | umls-concept:C0021759 | lld:lifeskim |
| pubmed-article:2970507 | lifeskim:mentions | umls-concept:C0003250 | lld:lifeskim |
| pubmed-article:2970507 | lifeskim:mentions | umls-concept:C0021075 | lld:lifeskim |
| pubmed-article:2970507 | lifeskim:mentions | umls-concept:C1527148 | lld:lifeskim |
| pubmed-article:2970507 | lifeskim:mentions | umls-concept:C0205369 | lld:lifeskim |
| pubmed-article:2970507 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:2970507 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:2970507 | pubmed:dateCreated | 1988-9-26 | lld:pubmed |
| pubmed-article:2970507 | pubmed:abstractText | Four rat mAb directed against mouse IL-5 have been characterized by their ability to remove and neutralize mouse IL-5 activity in various bioassays. All four mAb absorbed IL-5 activity from solution. Although all were able to neutralize mouse IL-5 bioactivity, two were significantly more effective. These two were also able to neutralize the activity of mouse IL-5 delivered to B cells during a cognate-linked interaction with a Th cell clone. A two-site sandwich ELISA specific for mouse IL-5 was developed by using pairs of mAb. The mouse IL-5 ELISA is capable of detecting natural or mouse rIL-5 in supernatants, crude bacterial lysates, and high concentrations of mouse serum, and has a detection limit of less than 20 pg. Two of these antibodies cross-reacted with and neutralized human rIL-5, and one of these was used for development of an ELISA for human IL-5. | lld:pubmed |
| pubmed-article:2970507 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2970507 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2970507 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:2970507 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2970507 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:2970507 | pubmed:issn | 0022-1767 | lld:pubmed |
| pubmed-article:2970507 | pubmed:author | pubmed-author:CoffmanR LRL | lld:pubmed |
| pubmed-article:2970507 | pubmed:author | pubmed-author:MosmannT RTR | lld:pubmed |
| pubmed-article:2970507 | pubmed:author | pubmed-author:O'GarraAA | lld:pubmed |
| pubmed-article:2970507 | pubmed:author | pubmed-author:BondM WMW | lld:pubmed |
| pubmed-article:2970507 | pubmed:author | pubmed-author:SchumacherJ... | lld:pubmed |
| pubmed-article:2970507 | pubmed:author | pubmed-author:ShraderBB | lld:pubmed |
| pubmed-article:2970507 | pubmed:author | pubmed-author:van... | lld:pubmed |
| pubmed-article:2970507 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2970507 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:2970507 | pubmed:volume | 141 | lld:pubmed |
| pubmed-article:2970507 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2970507 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2970507 | pubmed:pagination | 1576-81 | lld:pubmed |
| pubmed-article:2970507 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
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| pubmed-article:2970507 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:2970507 | pubmed:articleTitle | The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme-linked immunosorbent. | lld:pubmed |
| pubmed-article:2970507 | pubmed:affiliation | Department of Immunology, DNAX Research Institute, Palo Alto, CA 94304-1140. | lld:pubmed |
| pubmed-article:2970507 | pubmed:publicationType | Journal Article | lld:pubmed |
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