Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1988-7-11
pubmed:abstractText
A biphasic pattern of collagen biosynthesis was found in the aortae of spontaneously hypertensive (SHR) rats; the time course of the rate of biosynthesis is similar to that described in the heart by Sen and Bumpus. In comparison to age-matched controls, collagen biosynthesis is elevated in the SHR rats, diminishes during the first fourteen weeks and rises again at the stage of established hypertension. In the period of established hypertension, the increased rate of collagen biosynthesis was associated with a pronounced rise of the collagen type I to type III ratio. On the other hand, in the pre-hypertensive stage, the proportion of collagen type III clearly exceeds the proportion of collagen type I in SHR rats.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0369-9463
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
33-7
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Collagen in the aortae of spontaneously hypertensive (SHR) rats.
pubmed:affiliation
Institute of Physiology, Czechoslovak Academy of Sciences, Prague.
pubmed:publicationType
Journal Article