Linked Life Data

2954849

Source:http://linkedlifedata.com/resource/pubmed/id/2954849

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1987-7-27
pubmed:abstractText
Nalm 6M1 cells, derived from an acute lymphoblastic leukemia of the non-T, non-B type, are known to possess characteristics of early B-lymphocytes. In order to determine whether these cells are able to differentiate along the granulocyte-monocyte pathway, they were cultured in diffusion chambers, and classified according to morphological, cytochemical and immunological criteria. On the basis of this characterization, Nalm 6M1 cells positively labeling with monoclonal anti-human granulocyte or monocyte-specific antibodies were observed in all cases. These immunological changes were accompanied by the appearance of cells positive for the naphthyl-AS-D-chloroacetate esterase reaction. However, no changes in the blast-like appearance of the cultured cells were seen. From these data, we conclude that Nalm 6M1 cells already committed to the B-cell lineage retain their capacity to develop cellular markers of the granulocyte-monocyte series.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0902-4441
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
156-61
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Myelo-monocytic differentiation potential of the CALLA-positive Nalm 6M1 cell line.
pubmed:publicationType
Journal Article