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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1986-11-28
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pubmed:abstractText |
A miniaturized technique to administer vasoactive substances iontophoretically into the human finger skin and to continuously assess the resulting reaction of the vessels is described. Cutaneous blood flow is measured with a laser Doppler flow-meter. The technique has been used in 9 healthy volunteers with norepinephrine as test substance. The described method is a convenient way to evaluate the effects of transdermally applied vasoactive substances in a semiquantitative way without risking central effects of the substance to influence the registered blood flow.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0022-202X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
87
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
634-6
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2945868-Fingers,
pubmed-meshheading:2945868-Humans,
pubmed-meshheading:2945868-Iontophoresis,
pubmed-meshheading:2945868-Lasers,
pubmed-meshheading:2945868-Norepinephrine,
pubmed-meshheading:2945868-Regional Blood Flow,
pubmed-meshheading:2945868-Rheology,
pubmed-meshheading:2945868-Skin
|
pubmed:year |
1986
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pubmed:articleTitle |
Laser Doppler flow-meter assessment of iontophoretically applied norepinephrine on human finger skin circulation.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|